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2.2. Applicability of the results in USA

The results of Cochrane reviews applicable to conditions with limited resources. There is a possibility that, regardless of location and conditions, test results will be similar. The review included trials conducted in various places, including Egypt and several other developing countries.
2.3. Application of intervention

Surveys suggest that the use of cytotec for induction of labor must be preceded by the conduct of clinical trials with good design to determine the appropriate dose and schedule appointment. The trials included in these reviews, doses and schedules were different. Maximum concentrations in plasma misoprostol acid, the active metabolite of misoprostol, reduced when eating and it can reduce the effectiveness of purchase misoprostol (4).

Misoprostol nedorogostoyasch, so it can be cheap impact in the hospital. In order to apply this effect on the level of the hospital, the drug must first be registered for obstetrical use. Recently, the WHO Expert Committee on the Selection and Use of Essential medicines including tablets of misoprostol in a dosage of 25 mg to your list and this event will allow, finally, the national list of essential medicines to include low-dose misoprostol in the method of induction of labor.
3. RESEARCH

Surveys suggest that there is a need for randomized clinical trials with the correct design to answer the question about the optimal dosage and schedule that ensures the effectiveness and safety. Require additional clinical studies to determine the optimal dosage regimen for buccal or sublingual method of administration, its relative efficacy and safety compared with other methods of administration and other methods of induction of labor, as well as its acceptability to women.